Sandbox Reserved 1164: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
Structurally, the N-terminal extracellular domain (<scene name='72/721535/Ecd/2'>ECD</scene>) and the 7TM comprise the signature seven helical structure that is involved in the signaling via coupling to heterotrimeric proteins that activate adenylate cyclase to increase the levels of intracellular cyclic AMP, and also heterotrimeric G proteins that increase inositol phosphate and intracellular calcium levels. | Structurally, the N-terminal extracellular domain (<scene name='72/721535/Ecd/2'>ECD</scene>) and the 7TM comprise the signature seven helical structure[[Image:Overall.png|170 px|right|thumb| ECD and 7TM of protein]] that is involved in the signaling via coupling to heterotrimeric proteins that activate adenylate cyclase to increase the levels of intracellular cyclic AMP, and also heterotrimeric G proteins that increase inositol phosphate and intracellular calcium levels. | ||
Binding Pocket | |||
[[Image:Lig.jpg|350 px|left|thumb|Amino Acid sequence of Glucagon]] | [[Image:Lig.jpg|350 px|left|thumb|Amino Acid sequence of Glucagon]] | ||
