Large T Antigen: Difference between revisions

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|


*Large T antigen
*Large T antigen; Domains – origin-binding 131-260; helicase 266-627


**[[1faf]] – MPVLTA N terminal – murine polyomavirus – NMR<BR />
**[[1faf]] – MPVLTA N terminal – murine polyomavirus – NMR<BR />
**[[1n25]], [[1svo]] – SVLTA helicase domain – SV40<br />
**[[1n25]], [[1svo]] – SVLTA helicase domain – SV40<br />
**[[2fuf]] - SVLTA DNA-binding domain<br />
**[[2fuf]], [[2ipr]], [[2itj]], [[2if9]], [[3qn2]] - SVLTA origin-binding domain<br />
**[[1tbd]], [[2tbd]] - SVLTA DNA-binding domain - NMR<BR />
**[[1tbd]], [[2tbd]] - SVLTA DNA-binding domain - NMR<BR />
**[[2ipr]], [[2itj]], [[2if9]], [[3qn2]] - SVLTA origin-binding domain<br />
**[[4lif]], [[4nbp]], [[4lmd]] - JpvLTA  origin-binding domain – JC polyomavirus<br />
**[[4lif]], [[4nbp]], [[4lmd]] - LTA origin-binding domain – JD polyomavirus<br />
**[[5cyn]] - JpvLTA  origin-binding domain (mutant)<br />
**[[5j40]] - JpvLTA helicase domain  (mutant)<br />
**[[5j47]], [[5j4v]], [[5j4y]] - JpvLTA helicase domain (mutant) + inhibitor<br />


*Large T antigen complex with DNA
*Large T antigen complex with DNA


**[[2itl]], [[2ntc]], [[3qk2]], [[2nl8]], [[4fgn]], [[4gdf]] - SVLTA origin-binding domain + DNA<br />
**[[2itl]], [[2ntc]], [[3qk2]], [[2nl8]], [[4fgn]], [[4gdf]], [[5d9i]] - SVLTA origin-binding domain + DNA<br />
**[[9f3t]] - SVLTA  helicase domain + DNA <br />
**[[1svl]] - SVLTA helicase domain + ADP
**[[1svm]] - SVLTA helicase domain + ATP
**[[4fb3]] - MPVLTA origin-binding domain + DNA<br />
**[[4fb3]] - MPVLTA origin-binding domain + DNA<br />
**[[3qfq]] - LTA origin-binding domain + DNA – Merkel cell polyomavirus<br />
**[[3qfq]] - McpLTA origin-binding domain + DNA – Merkel cell polyomavirus
**[[1svl]] - SVLTA helicase domain + ADP<br />
**[[9exd]] - BpvLTA + ATP – Betapolyoma virus – Cryo EM<br />
**[[1svm]] - SVLTA helicase domain + ATP
**[[9evh]] - BpvLTA + ADP + DNA – Cryo EM<br />
**[[9f3u]], [[9f74]], [[9f7n]], [[9f9o]], [[9fa1]], [[9fa2]], [[9fb6]], [[9kae]], [[9kak]] - BpvLTA origin-binding domain + DNA – Cryo EM<br />


*Large T antigen complex with protein
*Large T antigen complex with protein
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**[[1z1d]] – SVLTA origin-binding domain + replication protein A32 C terminal<br />
**[[1z1d]] – SVLTA origin-binding domain + replication protein A32 C terminal<br />
**[[2h1l]] - SVLTA helicase domain + p53 DNA-binding domain<br />
**[[2h1l]] - SVLTA helicase domain + p53 DNA-binding domain<br />
**[[1gh6]] – SVLTA + retinoblastoma protein <br />
**[[1gh6]] – SVLTA 7-117 + retinoblastoma protein  
**[[4e2i]] – SVLTA + DNA polymerase α subunit<br />
**[[4e2i]] – SVLTA origin-binding domain + DNA polymerase α subunit<br />


*Large T antigen peptide complex with protein
*Large T antigen peptide complex with protein


**[[1bk6]], [[1ejl]], [[1q1s]], [[1q1t]] – SVLTA peptide + karyopherin α
**[[1bk6]], [[1ejl]], [[1q1s]], [[1q1t]] – SVLTA peptide 110-133 + karyopherin α<br />
**[[4rxh]] – SVLTA 125-132 + importin α subunit<br />
**[[8tur]] – McLTA 274-308 + importin α subunit<br />
**[[8sud]] – JpvLTA 111-133 + importin α subunit<br />
**[[8tuq]] – LTA 124-144 + importin α subunit – STL polyomavirus<br />
 
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== References ==
== References ==
{{reflist}}
{{reflist}}
[[Category:Topic Page]]
[[Category:Topic Page]]
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