4wn0: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:


==Xenopus laevis embryonic epidermal lectin in complex with glycerol phosphate==
==Xenopus laevis embryonic epidermal lectin in complex with glycerol phosphate==
<StructureSection load='4wn0' size='340' side='right' caption='[[4wn0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4wn0' size='340' side='right'caption='[[4wn0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4wn0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WN0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4wn0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WN0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G3P:SN-GLYCEROL-3-PHOSPHATE'>G3P</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wmo|4wmo]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G3P:SN-GLYCEROL-3-PHOSPHATE'>G3P</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wn0 OCA], [http://pdbe.org/4wn0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wn0 RCSB], [http://www.ebi.ac.uk/pdbsum/4wn0 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wn0 OCA], [https://pdbe.org/4wn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wn0 RCSB], [https://www.ebi.ac.uk/pdbsum/4wn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wn0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ITLN1_XENLA ITLN1_XENLA] Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed:26755729). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf) and D-phosphoglycerol-modified glycans (PubMed:26755729). Binds to S.pneumoniae serotypes with glycans that contain beta-linked D-galactofuranose (beta-Galf) and with D-phosphoglycerol-modified glycans (PubMed:26755729). Can bind a variety of monosaccharides (in vitro) (PubMed:15537792). Probably plays a role in the defense system against microorganisms (Probable).<ref>PMID:15537792</ref> <ref>PMID:26755729</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Forest, K T]]
[[Category: Large Structures]]
[[Category: Kiessling, L L]]
[[Category: Xenopus laevis]]
[[Category: Wangkanont, K]]
[[Category: Forest KT]]
[[Category: Calcium]]
[[Category: Kiessling LL]]
[[Category: Carbohydrate-binding protein]]
[[Category: Wangkanont K]]
[[Category: Fibrinogen-like domain]]
[[Category: Glycerol phosphate]]
[[Category: Innate immunity]]
[[Category: Lectin]]
[[Category: Microbial epitope]]
[[Category: Sugar binding protein]]
[[Category: Trimer]]
[[Category: X-type lectin]]
Retrieved from "https://proteopedia.org/4wn0"