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==MBX3132 bound structure of bacterial efflux pump.==
==MBX3132 bound structure of bacterial efflux pump.==
<StructureSection load='5enq' size='340' side='right' caption='[[5enq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5enq' size='340' side='right'caption='[[5enq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5enq]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ENQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ENQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5enq]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ENQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ENQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5QE:~{N}-[4-[2-[[5-CYANO-8-[(2~{S},6~{R})-2,6-DIMETHYLMORPHOLIN-4-YL]-3,3-DIMETHYL-1,4-DIHYDROPYRANO[3,4-C]PYRIDIN-6-YL]SULFANYL]ETHYL]PHENYL]ETHANAMIDE'>5QE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5enq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5enq OCA], [http://pdbe.org/5enq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5enq RCSB], [http://www.ebi.ac.uk/pdbsum/5enq PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5QE:~{N}-[4-[2-[[5-CYANO-8-[(2~{S},6~{R})-2,6-DIMETHYLMORPHOLIN-4-YL]-3,3-DIMETHYL-1,4-DIHYDROPYRANO[3,4-C]PYRIDIN-6-YL]SULFANYL]ETHYL]PHENYL]ETHANAMIDE'>5QE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5enq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5enq OCA], [https://pdbe.org/5enq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5enq RCSB], [https://www.ebi.ac.uk/pdbsum/5enq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5enq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI]] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ornik, A R]]
[[Category: Escherichia coli K-12]]
[[Category: Pos, K M]]
[[Category: Large Structures]]
[[Category: Sjuts, H]]
[[Category: Synthetic construct]]
[[Category: Efflux pump]]
[[Category: Ornik AR]]
[[Category: Transport protein]]
[[Category: Pos KM]]
[[Category: Sjuts H]]
Retrieved from "https://proteopedia.org/5enq"