5dv2: Difference between revisions
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==Crystal structure of human CNOT6L in complex with cytidine-5'-monophosphate== | |||
<StructureSection load='5dv2' size='340' side='right'caption='[[5dv2]], [[Resolution|resolution]] 2.07Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5dv2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DV2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene></td></tr> | ||
[[Category: Bartlam | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dv2 OCA], [https://pdbe.org/5dv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dv2 RCSB], [https://www.ebi.ac.uk/pdbsum/5dv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dv2 ProSAT]</span></td></tr> | ||
[[Category: Zhang | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CNO6L_HUMAN CNO6L_HUMAN] Plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA.<ref>PMID:17452450</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Bartlam M]] | |||
[[Category: Zhang Q]] | |||
Latest revision as of 09:10, 20 March 2024
Crystal structure of human CNOT6L in complex with cytidine-5'-monophosphate
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