5ilh: Difference between revisions

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New page: '''Unreleased structure''' The entry 5ilh is ON HOLD until Paper Publication Authors: Koo, H.J., Louie, G.V., Xu, Y., Bowman, M., Noel, J.P. Description: [[Category: Unreleased Struct...
 
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'''Unreleased structure'''


The entry 5ilh is ON HOLD  until Paper Publication
==Tobacco 5-epi-aristolochene synthase with CAPSO buffer molecule and Ca2+ ions==
 
<StructureSection load='5ilh' size='340' side='right'caption='[[5ilh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
Authors: Koo, H.J., Louie, G.V., Xu, Y., Bowman, M., Noel, J.P.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5ilh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ILH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ILH FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3CX:(2S)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3CX</scene>, <scene name='pdbligand=3FX:(2R)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3FX</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
[[Category: Louie, G.V]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ilh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ilh OCA], [https://pdbe.org/5ilh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ilh RCSB], [https://www.ebi.ac.uk/pdbsum/5ilh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ilh ProSAT]</span></td></tr>
[[Category: Koo, H.J]]
</table>
[[Category: Xu, Y]]
== Function ==
[[Category: Bowman, M]]
[https://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.
[[Category: Noel, J.P]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Nicotiana tabacum]]
[[Category: Bowman M]]
[[Category: Koo HJ]]
[[Category: Louie GV]]
[[Category: Noel JP]]
[[Category: Xu Y]]
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