5ilk: Difference between revisions
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New page: '''Unreleased structure''' The entry 5ilk is ON HOLD until Paper Publication Authors: Koo, H.J., Louie, G.V., Xu, Y., Bowman, M., Noel, J.P. Description: [[Category: Unreleased Struct... |
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==Tobacco 5-epi-aristolochene synthase with partial density from MOPSO or BIS-TRIS buffer molecule in the active site== | |||
<StructureSection load='5ilk' size='340' side='right'caption='[[5ilk]], [[Resolution|resolution]] 2.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ilk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ILK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ILK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ilk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ilk OCA], [https://pdbe.org/5ilk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ilk RCSB], [https://www.ebi.ac.uk/pdbsum/5ilk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ilk ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Koo | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Nicotiana tabacum]] | |||
[[Category: Bowman M]] | |||
[[Category: Koo HJ]] | |||
[[Category: Louie GV]] | |||
[[Category: Noel JP]] | |||
[[Category: Xu Y]] | |||
Latest revision as of 14:00, 30 August 2023
Tobacco 5-epi-aristolochene synthase with partial density from MOPSO or BIS-TRIS buffer molecule in the active site
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