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'''Unreleased structure'''


The entry 5itv is ON HOLD  until Paper Publication
==Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase in complex with NADH==
 
<StructureSection load='5itv' size='340' side='right'caption='[[5itv]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
Authors: Perinbam, K., Balaram, H., Row, T.N.G., Gopal, B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5itv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ITV FirstGlance]. <br>
Description: Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase in complex with NADH
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr>
[[Category: Perinbam, K]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5itv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5itv OCA], [https://pdbe.org/5itv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5itv RCSB], [https://www.ebi.ac.uk/pdbsum/5itv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5itv ProSAT]</span></td></tr>
[[Category: Balaram, H]]
</table>
[[Category: Gopal, B]]
== Function ==
[[Category: Row, T.N.G]]
[https://www.uniprot.org/uniprot/BACC_BACSU BACC_BACSU] Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the dehydrogenation of the C7-hydroxyl group in the 4S-tetrahydrotyrosine (4S-H4Tyr) to yield anticapsin (epoxycyclohexanonyl-Ala). It is not able to oxidize the 4R-H4Tyr diastereomer and the dihydrobacilysin dipeptide (L-Ala-4S-H4Tyr dipeptide).<ref>PMID:15609023</ref> <ref>PMID:23317005</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Large Structures]]
[[Category: Balaram H]]
[[Category: Gopal B]]
[[Category: Perinbam K]]
[[Category: Row TNG]]
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