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==Crystal structure of JmjC domain of human histone demethylase UTY in complex with N05859b==
==Crystal structure of JmjC domain of human histone demethylase UTY in complex with N05859b==
<StructureSection load='5fxv' size='340' side='right' caption='[[5fxv]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
<StructureSection load='5fxv' size='340' side='right'caption='[[5fxv]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fxv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FXV FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FXV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MN1:4-CARBOXYPIPERIDINE'>MN1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fxw|5fxw]], [[5fxx|5fxx]], [[5fxz|5fxz]], [[5fy0|5fy0]], [[5fy1|5fy1]], [[5fy4|5fy4]], [[5fy5|5fy5]], [[5fy7|5fy7]], [[5fy8|5fy8]], [[5fy9|5fy9]], [[5fyb|5fyb]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MN1:4-CARBOXYPIPERIDINE'>MN1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fxv OCA], [http://pdbe.org/5fxv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fxv RCSB], [http://www.ebi.ac.uk/pdbsum/5fxv PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fxv OCA], [https://pdbe.org/5fxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fxv RCSB], [https://www.ebi.ac.uk/pdbsum/5fxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fxv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN]] Histone demethylase (By similarity).  
[https://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN] Histone demethylase (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Homo sapiens]]
[[Category: Bountra, C]]
[[Category: Large Structures]]
[[Category: Delft, F von]]
[[Category: Arrowsmith CH]]
[[Category: Edwards, A]]
[[Category: Bountra C]]
[[Category: Gileadi, C]]
[[Category: Edwards A]]
[[Category: Johansson, C]]
[[Category: Gileadi C]]
[[Category: Krojer, T]]
[[Category: Johansson C]]
[[Category: Kupinska, K]]
[[Category: Krojer T]]
[[Category: Nowak, R]]
[[Category: Kupinska K]]
[[Category: Oerum, S]]
[[Category: Nowak R]]
[[Category: Oppermann, U]]
[[Category: Oerum S]]
[[Category: Pearce, N M]]
[[Category: Oppermann U]]
[[Category: Srikannathasan, V]]
[[Category: Pearce NM]]
[[Category: Fragment soaking]]
[[Category: Srikannathasan V]]
[[Category: Pandda]]
[[Category: Von Delft F]]
[[Category: Transferase]]
[[Category: X-ray fragment screening]]

Latest revision as of 13:31, 26 July 2023

Crystal structure of JmjC domain of human histone demethylase UTY in complex with N05859b

5fxv, resolution 1.91Å

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