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==Crystal structure of JmjC domain of human histone demethylase UTY in complex with oxaloacetate==
==Crystal structure of JmjC domain of human histone demethylase UTY in complex with oxaloacetate==
<StructureSection load='5fxx' size='340' side='right' caption='[[5fxx]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
<StructureSection load='5fxx' size='340' side='right'caption='[[5fxx]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fxx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FXX FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fxx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FXX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fxv|5fxv]], [[5fxw|5fxw]], [[5fxz|5fxz]], [[5fy0|5fy0]], [[5fy1|5fy1]], [[5fy4|5fy4]], [[5fy5|5fy5]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fxx OCA], [http://pdbe.org/5fxx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fxx RCSB], [http://www.ebi.ac.uk/pdbsum/5fxx PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fxx OCA], [https://pdbe.org/5fxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fxx RCSB], [https://www.ebi.ac.uk/pdbsum/5fxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fxx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN]] Histone demethylase (By similarity).  
[https://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN] Histone demethylase (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Homo sapiens]]
[[Category: Bountra, C]]
[[Category: Large Structures]]
[[Category: Delft, F von]]
[[Category: Arrowsmith CH]]
[[Category: Edwards, A]]
[[Category: Bountra C]]
[[Category: Gileadi, C]]
[[Category: Edwards A]]
[[Category: Johansson, C]]
[[Category: Gileadi C]]
[[Category: Krojer, T]]
[[Category: Johansson C]]
[[Category: Kupinska, K]]
[[Category: Krojer T]]
[[Category: Nowak, R]]
[[Category: Kupinska K]]
[[Category: Oppermann, U]]
[[Category: Nowak R]]
[[Category: Tca intermediate]]
[[Category: Oppermann U]]
[[Category: Transferase]]
[[Category: Von Delft F]]

Latest revision as of 13:31, 26 July 2023

Crystal structure of JmjC domain of human histone demethylase UTY in complex with oxaloacetate

5fxx, resolution 1.99Å

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