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==1.9 Angstrom Crystal Structure of NS5 Methyl Transferase from Dengue Virus 1 in Complex with S-Adenosylmethionine and Beta-D-Fructopyranose.==
==1.9 Angstrom Crystal Structure of NS5 Methyl Transferase from Dengue Virus 1 in Complex with S-Adenosylmethionine and Beta-D-Fructopyranose.==
<StructureSection load='5ikm' size='340' side='right' caption='[[5ikm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5ikm' size='340' side='right'caption='[[5ikm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ikm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IKM FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ikm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IKM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDF:BETA-D-FRUCTOPYRANOSE'>BDF</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BDF:BETA-D-FRUCTOPYRANOSE'>BDF</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ikm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ikm OCA], [http://pdbe.org/5ikm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ikm RCSB], [http://www.ebi.ac.uk/pdbsum/5ikm PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ikm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ikm OCA], [https://pdbe.org/5ikm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ikm RCSB], [https://www.ebi.ac.uk/pdbsum/5ikm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ikm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/I6XG39_9FLAV I6XG39_9FLAV]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Anderson, W F]]
[[Category: Dengue virus 1]]
[[Category: Large Structures]]
[[Category: Anderson WF]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Dubrovska, I]]
[[Category: Dubrovska I]]
[[Category: Flores, K]]
[[Category: Flores K]]
[[Category: Kwon, K]]
[[Category: Kwon K]]
[[Category: Minasov, G]]
[[Category: Minasov G]]
[[Category: Shatsman, S]]
[[Category: Shatsman S]]
[[Category: Shuvalova, L]]
[[Category: Shuvalova L]]
[[Category: Winsor, J]]
[[Category: Winsor J]]
[[Category: Beta-d-fructopyranose]]
[[Category: Csgid]]
[[Category: Dengue virus 1]]
[[Category: Ns5 methyl transferase]]
[[Category: S-adenosylmethionine]]
[[Category: Transferase]]

Latest revision as of 13:58, 30 August 2023

1.9 Angstrom Crystal Structure of NS5 Methyl Transferase from Dengue Virus 1 in Complex with S-Adenosylmethionine and Beta-D-Fructopyranose.

5ikm, resolution 1.90Å

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