5dhm: Difference between revisions

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==Crystal structure of the fimbrial protein Mfa4 from Porphyromonas gingivalis==
==Crystal structure of the fimbrial protein Mfa4 from Porphyromonas gingivalis==
<StructureSection load='5dhm' size='340' side='right' caption='[[5dhm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5dhm' size='340' side='right'caption='[[5dhm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5dhm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DHM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DHM FirstGlance]. <br>
<table><tr><td colspan='2'>[[5dhm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis_ATCC_33277 Porphyromonas gingivalis ATCC 33277]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DHM FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhm OCA], [http://pdbe.org/5dhm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dhm RCSB], [http://www.ebi.ac.uk/pdbsum/5dhm PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhm OCA], [https://pdbe.org/5dhm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dhm RCSB], [https://www.ebi.ac.uk/pdbsum/5dhm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MFA4_PORG3 MFA4_PORG3] Tip subunit of the minor fimbriae. These filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome (PubMed:19589838, PubMed:26001707). They play an important role in invasion of periodontal tissues and are recognized as major virulence factors (Probable).<ref>PMID:19589838</ref> <ref>PMID:26001707</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hall, M]]
[[Category: Large Structures]]
[[Category: Kloppsteck, P]]
[[Category: Porphyromonas gingivalis ATCC 33277]]
[[Category: Persson, K]]
[[Category: Hall M]]
[[Category: Adhesin]]
[[Category: Kloppsteck P]]
[[Category: Cell adhesion]]
[[Category: Persson K]]
[[Category: Fimbria]]
[[Category: Periodontitis]]
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