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==Crystal structure of Mmi1 YTH domain==
==Crystal structure of Mmi1 YTH domain==
<StructureSection load='5dnp' size='340' side='right' caption='[[5dnp]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5dnp' size='340' side='right'caption='[[5dnp]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5dnp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DNP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DNP FirstGlance]. <br>
<table><tr><td colspan='2'>[[5dnp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DNP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DNP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dno|5dno]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dnp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dnp OCA], [http://pdbe.org/5dnp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dnp RCSB], [http://www.ebi.ac.uk/pdbsum/5dnp PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dnp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dnp OCA], [https://pdbe.org/5dnp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dnp RCSB], [https://www.ebi.ac.uk/pdbsum/5dnp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dnp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MMI1_SCHPO MMI1_SCHPO]] RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs (By similarity). Required for elemination of certain meiosis-specific mRNAs in an early event following transcription. May bind to the cis-acting region (DSR) of the mRNA, activating the nuclear exosome which may lead to the degradation of the transcript from the 3' region (PubMed:16823445).[UniProtKB:Q06390]<ref>PMID:16823445</ref>
[https://www.uniprot.org/uniprot/MMI1_SCHPO MMI1_SCHPO] RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs (By similarity). Required for elemination of certain meiosis-specific mRNAs in an early event following transcription. May bind to the cis-acting region (DSR) of the mRNA, activating the nuclear exosome which may lead to the degradation of the transcript from the 3' region (PubMed:16823445).[UniProtKB:Q06390]<ref>PMID:16823445</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Shi, Y Y]]
[[Category: Large Structures]]
[[Category: Wang, C Y]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Wu, J H]]
[[Category: Shi YY]]
[[Category: Zhu, Y W]]
[[Category: Wang CY]]
[[Category: Rna binding]]
[[Category: Wu JH]]
[[Category: Rna binding protein]]
[[Category: Zhu YW]]
Retrieved from "https://proteopedia.org/5dnp"