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==Crystal structure of Trypanosoma brucei macrodomain in complex with ADP-ribose==
==Crystal structure of Trypanosoma brucei macrodomain in complex with ADP-ribose==
<StructureSection load='5fsy' size='340' side='right' caption='[[5fsy]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5fsy' size='340' side='right'caption='[[5fsy]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fsy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FSY FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fsy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FSY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AR6:[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL+[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL]+HYDROGEN+PHOSPHATE'>AR6</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fsu|5fsu]], [[5fsv|5fsv]], [[5fsx|5fsx]], [[5fsz|5fsz]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AR6:[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL+[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL]+HYDROGEN+PHOSPHATE'>AR6</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fsy OCA], [http://pdbe.org/5fsy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fsy RCSB], [http://www.ebi.ac.uk/pdbsum/5fsy PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fsy OCA], [https://pdbe.org/5fsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fsy RCSB], [https://www.ebi.ac.uk/pdbsum/5fsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fsy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C9ZP98_TRYB9 C9ZP98_TRYB9]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Haikarainen, T]]
[[Category: Large Structures]]
[[Category: Lehtio, L]]
[[Category: Trypanosoma brucei]]
[[Category: Adp-ribose binding]]
[[Category: Haikarainen T]]
[[Category: Hydrolase]]
[[Category: Lehtio L]]
[[Category: Macrodomain]]

Latest revision as of 13:22, 26 July 2023

Crystal structure of Trypanosoma brucei macrodomain in complex with ADP-ribose

5fsy, resolution 1.70Å

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