4rvx: Difference between revisions
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==Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL079== | ==Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL079== | ||
<StructureSection load='4rvx' size='340' side='right' caption='[[4rvx]], [[Resolution|resolution]] 1.96Å' scene=''> | <StructureSection load='4rvx' size='340' side='right'caption='[[4rvx]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4rvx]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVX OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4rvx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RVX FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=79G:(4S)-4-AMINO-N-[(2S,3S)-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}-1-PHENYLBUTAN-2-YL]-3,4-DIHYDRO-2H-CHROMENE-6-CARBOXAMIDE'>79G</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.955Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=79G:(4S)-4-AMINO-N-[(2S,3S)-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}-1-PHENYLBUTAN-2-YL]-3,4-DIHYDRO-2H-CHROMENE-6-CARBOXAMIDE'>79G</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvx OCA], [https://pdbe.org/4rvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rvx RCSB], [https://www.ebi.ac.uk/pdbsum/4rvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rvx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q9J006_9HIV1 Q9J006_9HIV1] | |||
==See Also== | |||
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Das D]] | ||
[[Category: Garimella H]] | |||
[[Category: | [[Category: Ghosh AK]] | ||
[[Category: | [[Category: Kaufman JD]] | ||
[[Category: | [[Category: Mitsuya H]] | ||
[[Category: | [[Category: Wingfield PT]] | ||
[[Category: | [[Category: Yedidi RS]] | ||
[[Category: | |||
Latest revision as of 12:56, 1 March 2024
Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL079
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