5jn0: Difference between revisions

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New page: '''Unreleased structure''' The entry 5jn0 is ON HOLD Authors: Description: Category: Unreleased Structures
 
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'''Unreleased structure'''


The entry 5jn0 is ON HOLD
==CRK-II SH2 domain==
<StructureSection load='5jn0' size='340' side='right'caption='[[5jn0]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5jn0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JN0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.677&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jn0 OCA], [https://pdbe.org/5jn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jn0 RCSB], [https://www.ebi.ac.uk/pdbsum/5jn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jn0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CRK_MOUSE CRK_MOUSE] The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.


Authors:
==See Also==
 
*[[Adapter molecule crk 3D structures|Adapter molecule crk 3D structures]]
Description:  
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cho J-H]]
Retrieved from "https://proteopedia.org/5jn0"