5jno: Difference between revisions
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==Crystal structure of the BD1-NTPR complex from BEND3 and PICH== | |||
<StructureSection load='5jno' size='340' side='right'caption='[[5jno]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5jno]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JNO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JNO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jno OCA], [https://pdbe.org/5jno PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jno RCSB], [https://www.ebi.ac.uk/pdbsum/5jno PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jno ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Montoya | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/BEND3_HUMAN BEND3_HUMAN] Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites (By similarity).[UniProtKB:Q6PAL0]<ref>PMID:21914818</ref> <ref>PMID:26100909</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Hickson ID]] | |||
[[Category: Mesa P]] | |||
[[Category: Montoya G]] | |||
[[Category: Pitchai G]] | |||
Latest revision as of 18:59, 20 September 2023
Crystal structure of the BD1-NTPR complex from BEND3 and PICH
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