5jr0: Difference between revisions
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==Domain 4 Segment 6 of voltage-gated sodium channel Nav1.4== | |||
<StructureSection load='5jr0' size='340' side='right'caption='[[5jr0]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5jr0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JR0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR, 10 models</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jr0 OCA], [https://pdbe.org/5jr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jr0 RCSB], [https://www.ebi.ac.uk/pdbsum/5jr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jr0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SCN4A_RAT SCN4A_RAT] This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.<ref>PMID:2559760</ref> | |||
==See Also== | |||
*[[Ion channels 3D structures|Ion channels 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Egawa A]] | |||
[[Category: Fujiwara T]] | |||
[[Category: Ikeda K]] | |||
[[Category: Niitsu A]] | |||
[[Category: Tachibana K]] | |||