5k58: Difference between revisions
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New page: '''Unreleased structure''' The entry 5k58 is ON HOLD Authors: Schumacher, M. Description: Structure of the K. pneumonia SlmA-DNA complex bound to the C-terminal of the cell division pr... |
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==Structure of the K. pneumonia SlmA-DNA complex bound to the C-terminal of the cell division protein FtsZ== | |||
<StructureSection load='5k58' size='340' side='right'caption='[[5k58]], [[Resolution|resolution]] 2.77Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5k58]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O139:H28_str._E24377A Escherichia coli O139:H28 str. E24377A] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K58 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.772Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k58 OCA], [https://pdbe.org/5k58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k58 RCSB], [https://www.ebi.ac.uk/pdbsum/5k58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k58 ProSAT]</span></td></tr> | ||
[[Category: Schumacher | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/SLMA_ECOLI SLMA_ECOLI] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.[HAMAP-Rule:MF_01839]<ref>PMID:15916962</ref> <ref>PMID:21113127</ref> <ref>PMID:21321206</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli O139:H28 str. E24377A]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Schumacher M]] | |||
Latest revision as of 12:39, 6 March 2024
Structure of the K. pneumonia SlmA-DNA complex bound to the C-terminal of the cell division protein FtsZ
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