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==Crystal Structure of Human SPLUNC1 Disulfide Mutant M3 (I76C, V214C)==
==Crystal Structure of Human SPLUNC1 Disulfide Mutant M3 (I76C, V214C)==
<StructureSection load='5i7j' size='340' side='right' caption='[[5i7j]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
<StructureSection load='5i7j' size='340' side='right'caption='[[5i7j]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5i7j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I7J FirstGlance]. <br>
<table><tr><td colspan='2'>[[5i7j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I7J FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i7l|5i7l]], [[5i7k|5i7k]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.544&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i7j OCA], [http://pdbe.org/5i7j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i7j RCSB], [http://www.ebi.ac.uk/pdbsum/5i7j PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i7j OCA], [https://pdbe.org/5i7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i7j RCSB], [https://www.ebi.ac.uk/pdbsum/5i7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i7j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BPIA1_HUMAN BPIA1_HUMAN]] May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways.<ref>PMID:11425234</ref>
[https://www.uniprot.org/uniprot/BPIA1_HUMAN BPIA1_HUMAN] May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways.<ref>PMID:11425234</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Redinbo, M R]]
[[Category: Homo sapiens]]
[[Category: Walton, W G]]
[[Category: Large Structures]]
[[Category: Antimicrobial protein]]
[[Category: Redinbo MR]]
[[Category: Innate pulmonary defense protein]]
[[Category: Walton WG]]
Retrieved from "https://proteopedia.org/5i7j"