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==2.25 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Neplanocin-A and NAD==
==2.25 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Neplanocin-A and NAD==
<StructureSection load='5jxw' size='340' side='right' caption='[[5jxw]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='5jxw' size='340' side='right'caption='[[5jxw]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5jxw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JXW FirstGlance]. <br>
<table><tr><td colspan='2'>[[5jxw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum Cryptosporidium parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JXW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6OS:NEPLANOCIN-A'>6OS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jpi|5jpi]], [[5hm8|5hm8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6OS:NEPLANOCIN-A'>6OS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteinase Adenosylhomocysteinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.1.1 3.3.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jxw OCA], [https://pdbe.org/5jxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jxw RCSB], [https://www.ebi.ac.uk/pdbsum/5jxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jxw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jxw OCA], [http://pdbe.org/5jxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jxw RCSB], [http://www.ebi.ac.uk/pdbsum/5jxw PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5CPH1_CRYPI Q5CPH1_CRYPI]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Adenosylhomocysteinase]]
[[Category: Cryptosporidium parvum]]
[[Category: Anderson, W F]]
[[Category: Large Structures]]
[[Category: Bishop, B]]
[[Category: Anderson WF]]
[[Category: Structural genomic]]
[[Category: Bishop B]]
[[Category: Dubrovska, I]]
[[Category: Dubrovska I]]
[[Category: Kiryukhina, O]]
[[Category: Kiryukhina O]]
[[Category: Kwon, K]]
[[Category: Kwon K]]
[[Category: Minasov, G]]
[[Category: Minasov G]]
[[Category: Shuvalova, L]]
[[Category: Shuvalova L]]
[[Category: Csgid]]
[[Category: Hydrolase]]
[[Category: Nad]]
[[Category: Neplanocin-a]]
[[Category: S-adenosylhomocysteinase]]