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==Structure of the Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant==
==Structure of the Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant==
<StructureSection load='4ckz' size='340' side='right' caption='[[4ckz]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
<StructureSection load='4ckz' size='340' side='right'caption='[[4ckz]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ckz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CKZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ckz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CKZ FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ckw|4ckw]], [[4ckx|4ckx]], [[4cky|4cky]], [[4cl0|4cl0]], [[4clm|4clm]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.52&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ckz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ckz OCA], [https://pdbe.org/4ckz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ckz RCSB], [https://www.ebi.ac.uk/pdbsum/4ckz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ckz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ckz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ckz OCA], [http://pdbe.org/4ckz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ckz RCSB], [http://www.ebi.ac.uk/pdbsum/4ckz PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]  
[https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
 
==See Also==
*[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 3-dehydroquinate dehydratase]]
[[Category: Large Structures]]
[[Category: Gonzalez-Bello, C]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Hawkins, A R]]
[[Category: Gonzalez-Bello C]]
[[Category: Lamb, H]]
[[Category: Hawkins AR]]
[[Category: Llamas-Saiz, A L]]
[[Category: Lamb H]]
[[Category: Maneiro, M]]
[[Category: Llamas-Saiz AL]]
[[Category: Otero, J M]]
[[Category: Maneiro M]]
[[Category: Peon, A]]
[[Category: Otero JM]]
[[Category: Raaij, M J.van]]
[[Category: Peon A]]
[[Category: Sedes, A]]
[[Category: Sedes A]]
[[Category: Bacterial protein]]
[[Category: Van Raaij MJ]]
[[Category: Inhibitor]]
[[Category: Lyase]]
[[Category: Protein binding]]
[[Category: Protein structure]]
[[Category: Shikimis acid pathway]]
[[Category: Substrate specificity]]
[[Category: Type 2 dehydroquinase]]

Latest revision as of 12:11, 20 December 2023

Structure of the Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant

4ckz, resolution 2.52Å

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