5b7j: Difference between revisions
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New page: '''Unreleased structure''' The entry 5b7j is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Structure model of Sap1-DNA complex== | |||
<StructureSection load='5b7j' size='340' side='right'caption='[[5b7j]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5b7j]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe] and [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B7J FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b7j OCA], [https://pdbe.org/5b7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b7j RCSB], [https://www.ebi.ac.uk/pdbsum/5b7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b7j ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SAP1_SCHPO SAP1_SCHPO] Binds to sequences required for mating-type switching. Makes a simultaneous contact with both the alpha and beta domains of the switch-activating site SAS1. Also binds to replication fork barrier 1 (RFB1) located within a 78 base pair sequence near the 3' end of the rRNA coding region. This leads to replication fork blockage. It binds the consensus sequence 5'-TA[AG]GCAGNTN[CT]AACG[AC]G-3'. Has a role in chromosome organization and integrity where it is involved in chromosome segregation. Has a role in sister chromatid cohesion and condensation. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Schizosaccharomyces pombe]] | |||
[[Category: Schizosaccharomyces pombe 972h-]] | |||
[[Category: Ding J]] | |||
[[Category: Hu Y]] | |||
[[Category: Jin C]] | |||
[[Category: Zhang Y]] | |||
Latest revision as of 07:21, 1 May 2024
Structure model of Sap1-DNA complex
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