5kkn: Difference between revisions
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==Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630== | |||
<StructureSection load='5kkn' size='340' side='right'caption='[[5kkn]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5kkn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KKN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6U3:2-[1-[(2~{R})-2-(2-METHOXYPHENYL)-2-(OXAN-4-YLOXY)ETHYL]-5-METHYL-6-(1,3-OXAZOL-2-YL)-2,4-BIS(OXIDANYLIDENE)THIENO[2,3-D]PYRIMIDIN-3-YL]-2-METHYL-PROPANAMIDE'>6U3</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kkn OCA], [https://pdbe.org/5kkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kkn RCSB], [https://www.ebi.ac.uk/pdbsum/5kkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kkn ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACACB_HUMAN ACACB_HUMAN] ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. | |||
==See Also== | |||
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Paul D]] | ||
[[Category: Tong L]] | |||
[[Category: Wang R]] | |||
Latest revision as of 12:40, 6 March 2024
Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630
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