5dya: Difference between revisions
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==Crystal structure of the human BRPF1 bromodomain in complex with SEED5== | ==Crystal structure of the human BRPF1 bromodomain in complex with SEED5== | ||
<StructureSection load='5dya' size='340' side='right' caption='[[5dya]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='5dya' size='340' side='right'caption='[[5dya]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5dya]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DYA OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5dya]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DYA FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GV:(2R)-2-ETHYL-3-OXO-1,2,3,4-TETRAHYDROQUINOXALINE-6-CARBOXYLIC+ACID'>5GV</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GV:(2R)-2-ETHYL-3-OXO-1,2,3,4-TETRAHYDROQUINOXALINE-6-CARBOXYLIC+ACID'>5GV</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dya OCA], [https://pdbe.org/5dya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dya RCSB], [https://www.ebi.ac.uk/pdbsum/5dya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dya ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5dya" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5dya" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Peregrin|Peregrin]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Caflisch A]] | ||
[[Category: | [[Category: Zhu J]] | ||
Latest revision as of 11:28, 10 January 2024
Crystal structure of the human BRPF1 bromodomain in complex with SEED5
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