5iot: Difference between revisions
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==Flavin-dependent thymidylate synthase R174A variant in complex with FAD and dUMP== | ==Flavin-dependent thymidylate synthase R174A variant in complex with FAD and dUMP== | ||
<StructureSection load='5iot' size='340' side='right' caption='[[5iot]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='5iot' size='340' side='right'caption='[[5iot]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5iot]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IOT OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5iot]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IOT FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iot OCA], [https://pdbe.org/5iot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iot RCSB], [https://www.ebi.ac.uk/pdbsum/5iot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iot ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/THYX_THEMA THYX_THEMA] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5iot" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5iot" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Thermotoga maritima MSB8]] | ||
[[Category: | [[Category: Bernard SM]] | ||
[[Category: | [[Category: Smith JL]] | ||
[[Category: | [[Category: Stull FW]] | ||
Latest revision as of 14:03, 30 August 2023
Flavin-dependent thymidylate synthase R174A variant in complex with FAD and dUMP
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