5ikw: Difference between revisions
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==Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor== | ==Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor== | ||
<StructureSection load='5ikw' size='340' side='right' caption='[[5ikw]], [[Resolution|resolution]] 2.41Å' scene=''> | <StructureSection load='5ikw' size='340' side='right'caption='[[5ikw]], [[Resolution|resolution]] 2.41Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5ikw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKW OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5ikw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IKW FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6BU:N-(6-{3-[(CYCLOPROPYLSULFONYL)AMINO]PHENYL}-1H-INDAZOL-3-YL)CYCLOPROPANECARBOXAMIDE'>6BU</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ikw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ikw OCA], [https://pdbe.org/5ikw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ikw RCSB], [https://www.ebi.ac.uk/pdbsum/5ikw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ikw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/BMP2K_HUMAN BMP2K_HUMAN] May be involved in osteoblast differentiation. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith | [[Category: Large Structures]] | ||
[[Category: Arruda | [[Category: Arrowsmith CH]] | ||
[[Category: Axtman | [[Category: Arruda P]] | ||
[[Category: Bountra | [[Category: Axtman A]] | ||
[[Category: Counago | [[Category: Bountra C]] | ||
[[Category: Drewry | [[Category: Counago RM]] | ||
[[Category: Edwards | [[Category: Drewry D]] | ||
[[Category: Elkins | [[Category: Edwards AM]] | ||
[[Category: Gileadi | [[Category: Elkins JM]] | ||
[[Category: Krojer | [[Category: Gileadi O]] | ||
[[Category: Krojer T]] | |||
[[Category: Savitsky | [[Category: Savitsky P]] | ||
[[Category: Sorrell | [[Category: Sorrell FJ]] | ||
[[Category: Wells | [[Category: Wells C]] | ||
[[Category: Willson | [[Category: Willson TM]] | ||
[[Category: Zhang | [[Category: Zhang C]] | ||
[[Category: Zuercher | [[Category: Zuercher W]] | ||
Latest revision as of 13:59, 30 August 2023
Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
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