5knx: Difference between revisions

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'''Unreleased structure'''


The entry 5knx is ON HOLD
==Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with {[(2-[(Hypoxanthin-9H-yl)methyl]propane-1,3-diyl)bis(oxy)]bis- (methylene)}diphosphonic Acid==
<StructureSection load='5knx' size='340' side='right'caption='[[5knx]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5knx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KNX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6WC:[2-[(6-oxidanylidene-1~{H}-purin-9-yl)methyl]-3-(phosphonomethoxy)propoxy]methylphosphonic+acid'>6WC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5knx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knx OCA], [https://pdbe.org/5knx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5knx RCSB], [https://www.ebi.ac.uk/pdbsum/5knx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5knx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HPRT_ECOLI HPRT_ECOLI] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine.


Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, Z., Guddat, L.W.
==See Also==
 
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
Description: Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with {[(2-[(Hypoxanthin-9H-yl)methyl]propane-1,3-diyl)bis(oxy)]bis-(methylene)}diphosphonic Acid
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Eng, W.S]]
[[Category: Escherichia coli]]
[[Category: Keough, D.T]]
[[Category: Large Structures]]
[[Category: Hockova, D]]
[[Category: Eng WS]]
[[Category: Janeba, Z]]
[[Category: Guddat LW]]
[[Category: Guddat, L.W]]
[[Category: Hockova D]]
[[Category: Janeba Z]]
[[Category: Keough DT]]
Retrieved from "https://proteopedia.org/5knx"