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==Crystal Structure at 3.4 A Resolution of Fully Glycosylated HIV-1 Clade G X1193.c1 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01==
==Crystal Structure at 3.4 A Resolution of Fully Glycosylated HIV-1 Clade G X1193.c1 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01==
<StructureSection load='5fyj' size='340' side='right' caption='[[5fyj]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
<StructureSection load='5fyj' size='340' side='right'caption='[[5fyj]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fyj]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FYJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fyj]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FYJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fyk|5fyk]], [[5fyl|5fyl]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fyj OCA], [http://pdbe.org/5fyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fyj RCSB], [http://www.ebi.ac.uk/pdbsum/5fyj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fyj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fyj OCA], [https://pdbe.org/5fyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fyj RCSB], [https://www.ebi.ac.uk/pdbsum/5fyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fyj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C6ZIG9_9HIV1 C6ZIG9_9HIV1]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5fyj" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5fyj" style="background-color:#fffaf0;"></div>
==See Also==
*[[Gp120 3D structures|Gp120 3D structures]]
*[[Gp41 3D Structures|Gp41 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Kwong, P D]]
[[Category: Homo sapiens]]
[[Category: Stewart-Jones, G B.E]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Thomas, P V]]
[[Category: Large Structures]]
[[Category: Zhou, T]]
[[Category: Kwong PD]]
[[Category: Envelope]]
[[Category: Stewart-Jones GBE]]
[[Category: Glycan]]
[[Category: Thomas PV]]
[[Category: Hiv]]
[[Category: Zhou T]]
[[Category: Trimer]]
[[Category: Viral protein]]

Latest revision as of 13:31, 26 July 2023

Crystal Structure at 3.4 A Resolution of Fully Glycosylated HIV-1 Clade G X1193.c1 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01

5fyj, resolution 3.11Å

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