5l03: Difference between revisions
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New page: '''Unreleased structure''' The entry 5l03 is ON HOLD Authors: Blain, J.M., Ghose, D., Gorman, J.L., Goshu, G.M., Ranieri, G., Zhao, L., Bode, B., Meganathan, R., Walter, R.L., Hagen, T.... |
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==Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to L-tryptophan hydroxamate== | |||
<StructureSection load='5l03' size='340' side='right'caption='[[5l03]], [[Resolution|resolution]] 1.47Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5l03]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L03 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L03 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.469Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6ZB:N-hydroxy-L-tryptophanamide'>6ZB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l03 OCA], [https://pdbe.org/5l03 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l03 RCSB], [https://www.ebi.ac.uk/pdbsum/5l03 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l03 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A069B2G5_BURPE A0A069B2G5_BURPE] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).[HAMAP-Rule:MF_00107][SAAS:SAAS00731896] | |||
==See Also== | |||
*[[MECDP synthase 3D structures|MECDP synthase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Burkholderia pseudomallei]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Blain JM]] | ||
[[Category: | [[Category: Bode B]] | ||
[[Category: | [[Category: Ghose D]] | ||
[[Category: | [[Category: Gorman JL]] | ||
[[Category: | [[Category: Goshu GM]] | ||
[[Category: | [[Category: Hagen TJ]] | ||
[[Category: | [[Category: Horn JR]] | ||
[[Category: Walter | [[Category: Meganathan R]] | ||
[[Category: | [[Category: Ranieri G]] | ||
[[Category: Walter RL]] | |||
[[Category: Zhao L]] | |||
Latest revision as of 16:03, 4 October 2023
Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to L-tryptophan hydroxamate
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