4gaw: Difference between revisions

<StructureSection load='4gaw' size='340' side='right'caption='[[4gaw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>

<table><tr><td colspan='2'>[[4gaw]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GAW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GAW FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gaw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gaw OCA], [https://pdbe.org/4gaw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gaw RCSB], [https://www.ebi.ac.uk/pdbsum/4gaw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gaw ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/GRAH_HUMAN GRAH_HUMAN] Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.<ref>PMID:22156497</ref> <ref>PMID:23269243</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Fan Z]]

[[Category: Li Q]]

[[Category: Sun F]]

[[Category: Tong L]]

[[Category: Wang L]]

[[Category: Wu L]]

[[Category: Zhang K]]