3l4n: Difference between revisions

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==Crystal structure of yeast monothiol glutaredoxin Grx6==
==Crystal structure of yeast monothiol glutaredoxin Grx6==
<StructureSection load='3l4n' size='340' side='right' caption='[[3l4n]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='3l4n' size='340' side='right'caption='[[3l4n]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3l4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L4N FirstGlance]. <br>
<table><tr><td colspan='2'>[[3l4n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L4N FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRX6, YDL010W, D2890 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l4n OCA], [https://pdbe.org/3l4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l4n RCSB], [https://www.ebi.ac.uk/pdbsum/3l4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l4n ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione-disulfide_reductase Glutathione-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.7 1.8.1.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l4n OCA], [http://pdbe.org/3l4n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l4n RCSB], [http://www.ebi.ac.uk/pdbsum/3l4n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l4n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLRX6_YEAST GLRX6_YEAST]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l4/3l4n_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l4/3l4n_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Glutathione-disulfide reductase]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Chen, Y]]
[[Category: Chen Y]]
[[Category: He, Y X]]
[[Category: He Y-X]]
[[Category: Jiang, Y L]]
[[Category: Jiang Y-L]]
[[Category: Luo, M]]
[[Category: Luo M]]
[[Category: Ma, X X]]
[[Category: Ma X-X]]
[[Category: Tang, Y J]]
[[Category: Tang Y-J]]
[[Category: Yu, J]]
[[Category: Yu J]]
[[Category: Zhang, R G]]
[[Category: Zhang R-G]]
[[Category: Zhou, C Z]]
[[Category: Zhou C-Z]]
[[Category: C-terminal domain of grx6]]
[[Category: Oxidoreductase]]

Latest revision as of 22:39, 26 March 2025

Crystal structure of yeast monothiol glutaredoxin Grx6

3l4n, resolution 1.50Å

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