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==Crystal Structure of SpoIIIAH and SpoIIQ Complex==
==Crystal Structure of SpoIIIAH and SpoIIQ Complex==
<StructureSection load='3uz0' size='340' side='right' caption='[[3uz0]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
<StructureSection load='3uz0' size='340' side='right'caption='[[3uz0]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3uz0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._bgsc_1a96 Bacillus subtilis subsp. subtilis str. bgsc 1a96]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UZ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UZ0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3uz0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._JH642 Bacillus subtilis subsp. subtilis str. JH642]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UZ0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">spoIIIAH, BSU24360 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=535025 Bacillus subtilis subsp. subtilis str. BGSC 1A96]), spoIIQ, ywnI, BSU36550 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=535025 Bacillus subtilis subsp. subtilis str. BGSC 1A96])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uz0 OCA], [https://pdbe.org/3uz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uz0 RCSB], [https://www.ebi.ac.uk/pdbsum/3uz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uz0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uz0 OCA], [http://pdbe.org/3uz0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3uz0 RCSB], [http://www.ebi.ac.uk/pdbsum/3uz0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3uz0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SP3AH_BACSU SP3AH_BACSU]] Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling.<ref>PMID:15574594</ref> <ref>PMID:15752199</ref> <ref>PMID:16164552</ref> <ref>PMID:16959571</ref> <ref>PMID:17824930</ref> <ref>PMID:18485064</ref> <ref>PMID:18812514</ref> [[http://www.uniprot.org/uniprot/SP2Q_BACSU SP2Q_BACSU]] Involved in forespore engulfment and required for anchoring membrane proteins on the forespore side of the septal membrane. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling.<ref>PMID:9140963</ref> <ref>PMID:10781563</ref> <ref>PMID:15882622</ref> <ref>PMID:15752199</ref> <ref>PMID:16164552</ref> <ref>PMID:16959571</ref> <ref>PMID:17824930</ref> <ref>PMID:18077456</ref> <ref>PMID:18485064</ref> <ref>PMID:18812514</ref> 
[https://www.uniprot.org/uniprot/SP3AH_BACSU SP3AH_BACSU] Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling.<ref>PMID:15574594</ref> <ref>PMID:15752199</ref> <ref>PMID:16164552</ref> <ref>PMID:16959571</ref> <ref>PMID:17824930</ref> <ref>PMID:18485064</ref> <ref>PMID:18812514</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis subsp. subtilis str. bgsc 1a96]]
[[Category: Bacillus subtilis subsp. subtilis str. JH642]]
[[Category: Dunham, C M]]
[[Category: Large Structures]]
[[Category: Maehigashi, T]]
[[Category: Dunham CM]]
[[Category: Meisner, J]]
[[Category: Maehigashi T]]
[[Category: Hybrid transporter]]
[[Category: Meisner J]]
[[Category: Membrane]]
[[Category: Sporulation]]
[[Category: Transport protein]]
Retrieved from "https://proteopedia.org/3uz0"