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==CRYSTAL STRUCTURE OF STREPTOCOCCUS SUIS DPR WITH COBALT==
==Crystal structure of Streptococcus suis Dpr with cobalt==
<StructureSection load='2xjm' size='340' side='right' caption='[[2xjm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2xjm' size='340' side='right'caption='[[2xjm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xjm]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43765 Atcc 43765]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XJM FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xjm]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_suis Streptococcus suis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XJM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1umn|1umn]], [[2bw1|2bw1]], [[2cf7|2cf7]], [[2ux1|2ux1]], [[2v15|2v15]], [[2xkq|2xkq]], [[2xjo|2xjo]], [[2xjn|2xjn]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xjm OCA], [http://pdbe.org/2xjm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xjm RCSB], [http://www.ebi.ac.uk/pdbsum/2xjm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xjm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xjm OCA], [https://pdbe.org/2xjm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xjm RCSB], [https://www.ebi.ac.uk/pdbsum/2xjm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xjm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPS_STRSU DPS_STRSU]] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It binds and incorporates Fe(2+) iron. Is responsible for hydrogen peroxide resistance. Does not bind DNA.  
[https://www.uniprot.org/uniprot/DPS_STRSU DPS_STRSU] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It binds and incorporates Fe(2+) iron. Is responsible for hydrogen peroxide resistance. Does not bind DNA.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Ferritin|Ferritin]]
*[[Ferritin 3D structures|Ferritin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 43765]]
[[Category: Large Structures]]
[[Category: Haataja, S]]
[[Category: Streptococcus suis]]
[[Category: Haikarainen, T]]
[[Category: Haataja S]]
[[Category: Nounesis, G]]
[[Category: Haikarainen T]]
[[Category: Papageorgiou, A C]]
[[Category: Nounesis G]]
[[Category: Stavros, P]]
[[Category: Papageorgiou AC]]
[[Category: Thanassoulas, A]]
[[Category: Stavros P]]
[[Category: Iron storage]]
[[Category: Thanassoulas A]]
[[Category: Metal-binding]]
[[Category: Oxidoreductase]]