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==Crystal structure of CRISPR associated protein==
==Crystal structure of CRISPR associated protein==
<StructureSection load='3s5u' size='340' side='right' caption='[[3s5u]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3s5u' size='340' side='right'caption='[[3s5u]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3s5u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis_atcc_4200 Enterococcus faecalis atcc 4200]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S5U FirstGlance]. <br>
<table><tr><td colspan='2'>[[3s5u]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_ATCC_4200 Enterococcus faecalis ATCC 4200]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S5U FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EFDG_01320 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=565642 Enterococcus faecalis ATCC 4200])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s5u OCA], [http://pdbe.org/3s5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3s5u RCSB], [http://www.ebi.ac.uk/pdbsum/3s5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3s5u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s5u OCA], [https://pdbe.org/3s5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s5u RCSB], [https://www.ebi.ac.uk/pdbsum/3s5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s5u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CSN2_ENTFL CSN2_ENTFL]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity). Binds dsDNA, binding is disrupted by EGTA.  
[https://www.uniprot.org/uniprot/CSN2_ENTFL CSN2_ENTFL] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity). Binds dsDNA, binding is disrupted by EGTA.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Enterococcus faecalis atcc 4200]]
[[Category: Enterococcus faecalis ATCC 4200]]
[[Category: Ke, A]]
[[Category: Large Structures]]
[[Category: Nam, K H]]
[[Category: Ke A]]
[[Category: Crispr]]
[[Category: Nam KH]]
[[Category: Crispr adaptation mechanism]]
[[Category: Dna binding protein]]
[[Category: Dsdna binding]]
[[Category: New spacer aquisition]]
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