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==Crystal structure of the complex formed between typeI ribosome inactivating protein and lactose at 2.1A resolution==
==Crystal structure of the complex formed between typeI ribosome inactivating protein and lactose at 2.1A resolution==
<StructureSection load='3njs' size='340' side='right' caption='[[3njs]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='3njs' size='340' side='right'caption='[[3njs]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3njs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NJS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NJS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3njs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NJS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NJS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LAT:BETA-LACTOSE'>LAT</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aha|1aha]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PRD_900004:beta-lactose'>PRD_900004</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3njs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3njs OCA], [https://pdbe.org/3njs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3njs RCSB], [https://www.ebi.ac.uk/pdbsum/3njs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3njs ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3njs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3njs OCA], [http://pdbe.org/3njs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3njs RCSB], [http://www.ebi.ac.uk/pdbsum/3njs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3njs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D9J2T9_MOMBA D9J2T9_MOMBA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nj/3njs_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nj/3njs_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Ribosome inactivating protein|Ribosome inactivating protein]]
*[[Ribosome inactivating protein 3D structures|Ribosome inactivating protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Momordica balsamina]]
[[Category: Momordica balsamina]]
[[Category: RRNA N-glycosylase]]
[[Category: Kaur P]]
[[Category: Kaur, P]]
[[Category: Kushwaha GS]]
[[Category: Kushwaha, G S]]
[[Category: Pandey N]]
[[Category: Pandey, N]]
[[Category: Sharma S]]
[[Category: Sharma, S]]
[[Category: Singh TP]]
[[Category: Singh, T P]]
[[Category: Sinha M]]
[[Category: Sinha, M]]
[[Category: Hydrolase]]
[[Category: Lactose]]
[[Category: Plant protein]]
[[Category: Rip]]
[[Category: Rna n-glycosidase]]

Latest revision as of 10:13, 6 November 2024

Crystal structure of the complex formed between typeI ribosome inactivating protein and lactose at 2.1A resolution

3njs, resolution 2.10Å

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