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==UDP-Glucose Pyrophosphorylase from Leishmania major in complex with UTP analog dUpCpp==
==UDP-Glucose Pyrophosphorylase from Leishmania major in complex with UTP analog dUpCpp==
<StructureSection load='4m28' size='340' side='right' caption='[[4m28]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='4m28' size='340' side='right'caption='[[4m28]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4m28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leima Leima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M28 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4m28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M28 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UPC:2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]METHYL}PHOSPHORYL]URIDINE'>UPC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oef|2oef]], [[2oeg|2oeg]], [[4m2a|4m2a]], [[4m2b|4m2b]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UPC:2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]METHYL}PHOSPHORYL]URIDINE'>UPC</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UGP, LMJF_18_0990 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5664 LEIMA])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m28 OCA], [https://pdbe.org/4m28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m28 RCSB], [https://www.ebi.ac.uk/pdbsum/4m28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m28 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UTP--glucose-1-phosphate_uridylyltransferase UTP--glucose-1-phosphate uridylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.9 2.7.7.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m28 OCA], [http://pdbe.org/4m28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m28 RCSB], [http://www.ebi.ac.uk/pdbsum/4m28 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m28 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4QDU3_LEIMA Q4QDU3_LEIMA]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Leima]]
[[Category: Large Structures]]
[[Category: UTP--glucose-1-phosphate uridylyltransferase]]
[[Category: Leishmania major]]
[[Category: Baruch, P]]
[[Category: Baruch P]]
[[Category: Fedorov, R]]
[[Category: Fedorov R]]
[[Category: Fuehring, J I]]
[[Category: Fuehring JI]]
[[Category: Gerardy-Schahn, R]]
[[Category: Gerardy-Schahn R]]
[[Category: Lamerz, A C]]
[[Category: Lamerz A-C]]
[[Category: Routier, F H]]
[[Category: Routier FH]]
[[Category: Nucleotidyltransferase]]
[[Category: Rossmann-like alpha/beta/alpha sandwich fold]]
[[Category: Transferase]]
[[Category: Udp-glucose pyrophosphorylase]]

Latest revision as of 16:30, 20 September 2023

UDP-Glucose Pyrophosphorylase from Leishmania major in complex with UTP analog dUpCpp

4m28, resolution 3.00Å

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