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==CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE FROM ESCHERICHIA COLI AT 2. 11 ANGSTROEM RESOLUTION==
==CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE FROM ESCHERICHIA COLI AT 2. 11 ANGSTROEM RESOLUTION==
<StructureSection load='4cvq' size='340' side='right' caption='[[4cvq]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
<StructureSection load='4cvq' size='340' side='right'caption='[[4cvq]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cvq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cvq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CVQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine_transaminase Alanine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.2 2.6.1.2] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvq OCA], [http://pdbe.org/4cvq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cvq RCSB], [http://www.ebi.ac.uk/pdbsum/4cvq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cvq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvq OCA], [https://pdbe.org/4cvq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cvq RCSB], [https://www.ebi.ac.uk/pdbsum/4cvq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cvq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ALAA_ECOL6 ALAA_ECOL6]] Involved in the biosynthesis of alanine (By similarity).  
[https://www.uniprot.org/uniprot/ALAA_ECOLI ALAA_ECOLI] Involved in the biosynthesis of alanine. Catalyzes the transamination of pyruvate by glutamate, leading to the formation of L-alanine and 2-oxoglutarate. Is also able to catalyze the reverse reaction.<ref>PMID:20729367</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alanine transaminase]]
[[Category: Escherichia coli K-12]]
[[Category: Coll, M]]
[[Category: Large Structures]]
[[Category: Fernandez, F J]]
[[Category: Coll M]]
[[Category: Garces, F]]
[[Category: Fernandez FJ]]
[[Category: Lopez-Estepa, M]]
[[Category: Garces F]]
[[Category: Penya-Soler, E]]
[[Category: Lopez-Estepa M]]
[[Category: Richardson, A J]]
[[Category: Penya-Soler E]]
[[Category: Rudd, K E]]
[[Category: Richardson AJ]]
[[Category: Vega, M C]]
[[Category: Rudd KE]]
[[Category: Amino acid metabolism]]
[[Category: Vega MC]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4cvq"