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==The Structure of the inactive mutant G153R of LptC from E. coli==
==The Structure of the inactive mutant G153R of LptC from E. coli==
<StructureSection load='4b54' size='340' side='right' caption='[[4b54]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='4b54' size='340' side='right'caption='[[4b54]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4b54]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B54 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4b54]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B54 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b54 OCA], [http://pdbe.org/4b54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b54 RCSB], [http://www.ebi.ac.uk/pdbsum/4b54 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b54 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b54 OCA], [https://pdbe.org/4b54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b54 RCSB], [https://www.ebi.ac.uk/pdbsum/4b54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b54 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/I2Z3T4_ECOLX I2Z3T4_ECOLX]] Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.[PIRNR:PIRNR028513]
[https://www.uniprot.org/uniprot/LPTC_ECOLI LPTC_ECOLI] Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. It facilitates the transfer of LPS from the inner membrane to a periplasmic chaperone, LptA.<ref>PMID:16765569</ref> <ref>PMID:18424520</ref> <ref>PMID:20720015</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Bolognesi, M]]
[[Category: Large Structures]]
[[Category: Gourlay, L J]]
[[Category: Bolognesi M]]
[[Category: Kahne, D]]
[[Category: Gourlay LJ]]
[[Category: Martorana, A M]]
[[Category: Kahne D]]
[[Category: Nardini, M]]
[[Category: Martorana AM]]
[[Category: Okuda, S]]
[[Category: Nardini M]]
[[Category: Polissi, A]]
[[Category: Okuda S]]
[[Category: Sperandeo, P]]
[[Category: Polissi A]]
[[Category: Villa, R]]
[[Category: Sperandeo P]]
[[Category: Inactive mutant]]
[[Category: Villa R]]
[[Category: Transport protein]]
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