4cw4: Difference between revisions

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==Crystal structure of the noncanonical ketosynthase FabY from P. aeruginosa==
==Crystal structure of the noncanonical ketosynthase FabY from P. aeruginosa==
<StructureSection load='4cw4' size='340' side='right' caption='[[4cw4]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
<StructureSection load='4cw4' size='340' side='right'caption='[[4cw4]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cw4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CW4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CW4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.349&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cw5|4cw5]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cw4 OCA], [http://pdbe.org/4cw4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cw4 RCSB], [http://www.ebi.ac.uk/pdbsum/4cw4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cw4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cw4 OCA], [https://pdbe.org/4cw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cw4 RCSB], [https://www.ebi.ac.uk/pdbsum/4cw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cw4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FABY_PSEAE FABY_PSEAE] Involved in the initiation of the fatty acid biosynthesis. Catalyzes the condensation of acetyl coenzyme A (acetyl-CoA) with malonyl-acyl carrier protein (ACP) to make the fatty acid synthesis (FAS) primer beta-acetoacetyl-ACP. It can also use short-chain acyl-CoA as substrates, including butyryl-CoA, and hexanoyl-CoA, but does not use any of the longer chain acyl-CoA substrates.<ref>PMID:22753059</ref> <ref>PMID:24145528</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bukhari, H S.T]]
[[Category: Large Structures]]
[[Category: Jakob, R P]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Maier, T]]
[[Category: Bukhari HST]]
[[Category: Fa]]
[[Category: Jakob RP]]
[[Category: Fatty acid synthase]]
[[Category: Maier T]]
[[Category: Ka]]
[[Category: Kas i/ii]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4cw4"