2rre: Difference between revisions
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==Structure and function of the N-terminal nucleolin binding domain of nuclear valocine containing protein like 2 (NVL2) harboring a nucleolar localization signal== | ==Structure and function of the N-terminal nucleolin binding domain of nuclear valocine containing protein like 2 (NVL2) harboring a nucleolar localization signal== | ||
<StructureSection load='2rre' size='340' side='right' caption='[[2rre | <StructureSection load='2rre' size='340' side='right'caption='[[2rre]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2rre]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2rre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RRE FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rre OCA], [https://pdbe.org/2rre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rre RCSB], [https://www.ebi.ac.uk/pdbsum/2rre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rre ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/NVL_MOUSE NVL_MOUSE] Participates in the assembly of the telomerase holoenzyme and effecting of telomerase activity via its interaction with TERT. Involved in both early and late stages of the pre-rRNA processing pathways. Spatiotemporally regulates 60S ribosomal subunit biogenesis in the nucleolus. Catalyzes the release of specific assembly factors, such as WDR74, from pre-60S ribosomal particles through the ATPase activity.[UniProtKB:O15381] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Fujiwara | [[Category: Mus musculus]] | ||
[[Category: Fujiwara | [[Category: Fujiwara K]] | ||
[[Category: Goda | [[Category: Fujiwara Y]] | ||
[[Category: Hiroaki | [[Category: Goda N]] | ||
[[Category: Iwaya | [[Category: Hiroaki H]] | ||
[[Category: Shirakawa | [[Category: Iwaya N]] | ||
[[Category: Tenno | [[Category: Shirakawa M]] | ||
[[Category: Tenno T]] | |||