1l1p: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1l1p.jpg|left|200px]]


{{Structure
==Solution Structure of the PPIase Domain from E. coli Trigger Factor==
|PDB= 1l1p |SIZE=350|CAPTION= <scene name='initialview01'>1l1p</scene>
<StructureSection load='1l1p' size='340' side='right'caption='[[1l1p]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1l1p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L1P FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l1p OCA], [https://pdbe.org/1l1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l1p RCSB], [https://www.ebi.ac.uk/pdbsum/1l1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l1p ProSAT], [https://www.topsan.org/Proteins/BSGI/1l1p TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l1p OCA], [http://www.ebi.ac.uk/pdbsum/1l1p PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1l1p RCSB]</span>
[https://www.uniprot.org/uniprot/TIG_ECOLI TIG_ECOLI] Involved in protein export. Acts as a chaperone by maintaining the newly synthesized secretory and non-secretory proteins in an open conformation. Binds to nascent polypeptide chains via ribosomal protein L23 (PubMed:12226666). Functions as a peptidyl-prolyl cis-trans isomerase in vitro, this activity is dispensible in vivo for chaperone activity.<ref>PMID:8633085</ref> <ref>PMID:8521806</ref> <ref>PMID:14726952</ref>
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Solution Structure of the PPIase Domain from E. coli Trigger Factor'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l1/1l1p_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
1L1P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L1P OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l1p ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Denisov A]]
[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
[[Category: Ekiel I]]
[[Category: Denisov, A.]]
[[Category: Gehring K]]
[[Category: Ekiel, I.]]
[[Category: Ghandi S]]
[[Category: Gehring, K.]]
[[Category: Kozlov G]]
[[Category: Ghandi, S.]]
[[Category: Perreault A]]
[[Category: Kozlov, G.]]
[[Category: Trempe J-F]]
[[Category: Perreault, A.]]
[[Category: Wong M]]
[[Category: Trempe, J F.]]
[[Category: Wong, M.]]
[[Category: bsgi]]
[[Category: mixed beta-alpha structure]]
[[Category: montreal-kingston bacterial structural genomics initiative]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:56:49 2008''