3uv3: Difference between revisions
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==Ec_IspH in complex with but-2-ynyl diphosphate (1086)== | ==Ec_IspH in complex with but-2-ynyl diphosphate (1086)== | ||
<StructureSection load='3uv3' size='340' side='right' caption='[[3uv3]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='3uv3' size='340' side='right'caption='[[3uv3]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3uv3]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3uv3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UV3 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0CM:BUT-2-YN-1-YL+TRIHYDROGEN+DIPHOSPHATE'>0CM</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uv3 OCA], [https://pdbe.org/3uv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uv3 RCSB], [https://www.ebi.ac.uk/pdbsum/3uv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uv3 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase|4-hydroxy-3-methylbut-2-enyl diphosphate reductase]] | *[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures|4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli K-12]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Bacher | [[Category: Bacher A]] | ||
[[Category: Eisenreich | [[Category: Eisenreich W]] | ||
[[Category: Groll | [[Category: Groll M]] | ||
[[Category: Oldfield | [[Category: Oldfield E]] | ||
[[Category: Schulz | [[Category: Schulz C]] | ||
[[Category: Span | [[Category: Span I]] | ||
[[Category: Wang | [[Category: Wang K]] | ||
[[Category: Wang | [[Category: Wang W]] | ||
[[Category: Zhang | [[Category: Zhang Y]] | ||
