4ixd: Difference between revisions
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==X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution== | ==X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution== | ||
<StructureSection load='4ixd' size='340' side='right' caption='[[4ixd]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='4ixd' size='340' side='right'caption='[[4ixd]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ixd]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4ixd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IXD FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1HV:4-(3-{4-[(3-AMINOPROPYL)CARBAMOYL]PHENYL}-1H-INDAZOL-1-YL)-N-METHYLBENZAMIDE'>1HV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1HV:4-(3-{4-[(3-AMINOPROPYL)CARBAMOYL]PHENYL}-1H-INDAZOL-1-YL)-N-METHYLBENZAMIDE'>1HV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ixd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixd OCA], [https://pdbe.org/4ixd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ixd RCSB], [https://www.ebi.ac.uk/pdbsum/4ixd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ixd ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. | ||
==See Also== | ==See Also== | ||
*[[Integrin|Integrin]] | *[[Integrin 3D structures|Integrin 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Kallen J]] | ||
Latest revision as of 15:32, 20 September 2023
X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution
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