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==Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) in complex with CDPME==
==Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) in complex with CDPME==
<StructureSection load='3pye' size='340' side='right' caption='[[3pye]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3pye' size='340' side='right'caption='[[3pye]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3pye]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PYE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PYE FirstGlance]. <br>
<table><tr><td colspan='2'>[[3pye]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PYE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PYE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDM:4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL'>CDM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pyd|3pyd]], [[3pyf|3pyf]], [[3pyg|3pyg]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDM:4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL'>CDM</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispE, Rv1011, MT1040, MTCI237.28 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pye OCA], [https://pdbe.org/3pye PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pye RCSB], [https://www.ebi.ac.uk/pdbsum/3pye PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pye ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-(cytidine_5'-diphospho)-2-C-methyl-D-erythritol_kinase 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.148 2.7.1.148] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pye OCA], [http://pdbe.org/3pye PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pye RCSB], [http://www.ebi.ac.uk/pdbsum/3pye PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pye ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ISPE_MYCTU ISPE_MYCTU]] Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.[HAMAP-Rule:MF_00061]  
[https://www.uniprot.org/uniprot/ISPE_MYCTU ISPE_MYCTU] Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.[HAMAP-Rule:MF_00061]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chen, X H]]
[[Category: Large Structures]]
[[Category: Liu, T]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Lou, Z Y]]
[[Category: Chen XH]]
[[Category: Rao, Z H]]
[[Category: Liu T]]
[[Category: Shan, S]]
[[Category: Lou ZY]]
[[Category: Zhao, H C]]
[[Category: Rao ZH]]
[[Category: 4-diphosphocytidyl-2-c-methyl-d-erythritol kinase]]
[[Category: Shan S]]
[[Category: Kinase]]
[[Category: Zhao HC]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3pye"