3t2n: Difference between revisions
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==Human hepsin protease in complex with the Fab fragment of an inhibitory antibody== | ==Human hepsin protease in complex with the Fab fragment of an inhibitory antibody== | ||
<StructureSection load='3t2n' size='340' side='right' caption='[[3t2n]], [[Resolution|resolution]] 2.55Å' scene=''> | <StructureSection load='3t2n' size='340' side='right'caption='[[3t2n]], [[Resolution|resolution]] 2.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3t2n]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3t2n]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T2N FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t2n OCA], [https://pdbe.org/3t2n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t2n RCSB], [https://www.ebi.ac.uk/pdbsum/3t2n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t2n ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HEPS_HUMAN HEPS_HUMAN] Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL.<ref>PMID:21875933</ref> <ref>PMID:15839837</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 22: | Line 20: | ||
==See Also== | ==See Also== | ||
*[[3D structures | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Auer | [[Category: Auer J]] | ||
[[Category: Cramer | [[Category: Cramer P]] | ||
[[Category: Dengl | [[Category: Dengl S]] | ||
[[Category: Duerr | [[Category: Duerr H]] | ||
[[Category: Georges | [[Category: Georges G]] | ||
[[Category: Hansen | [[Category: Hansen S]] | ||
[[Category: Hartl | [[Category: Hartl C]] | ||
[[Category: Huang | [[Category: Huang K-S]] | ||
[[Category: Jennewein | [[Category: Jennewein S]] | ||
[[Category: Kaluza | [[Category: Kaluza K]] | ||
[[Category: Kohnert | [[Category: Kohnert U]] | ||
[[Category: Koschubs | [[Category: Koschubs T]] | ||
[[Category: Kostrewa | [[Category: Kostrewa D]] | ||
[[Category: Lanzendoerfer | [[Category: Lanzendoerfer M]] | ||
[[Category: Mundigl | [[Category: Mundigl O]] | ||
[[Category: Ries | [[Category: Ries S]] | ||
[[Category: Stern | [[Category: Stern A]] | ||
