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==Crystal structure of carboxynorspermidine decarboxylase complexed with Norspermidine from Campylobacter jejuni==
==Crystal structure of carboxynorspermidine decarboxylase complexed with Norspermidine from Campylobacter jejuni==
<StructureSection load='3n29' size='340' side='right' caption='[[3n29]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3n29' size='340' side='right'caption='[[3n29]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3n29]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Camj8 Camj8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N29 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3n29]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N29 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N29 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NSD:N-(3-AMINOPROPYL)PROPANE-1,3-DIAMINE'>NSD</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3n2o|3n2o]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NSD:N-(3-AMINOPROPYL)PROPANE-1,3-DIAMINE'>NSD</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">carboxynorspermidine decarboxylase, CJJHB9313_1507, nspC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=407148 CAMJ8])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n29 OCA], [https://pdbe.org/3n29 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n29 RCSB], [https://www.ebi.ac.uk/pdbsum/3n29 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n29 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n29 OCA], [http://pdbe.org/3n29 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3n29 RCSB], [http://www.ebi.ac.uk/pdbsum/3n29 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3n29 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NSPC_CAMJ8 NSPC_CAMJ8] Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine in vitro. In vivo, responsible for synthesizing spermidine, but not sym-norspermidine.<ref>PMID:20534592</ref> <ref>PMID:22025614</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/3n29_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/3n29_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camj8]]
[[Category: Campylobacter jejuni subsp. jejuni 81116]]
[[Category: Deng, X]]
[[Category: Large Structures]]
[[Category: Goldsmith, E J]]
[[Category: Deng X]]
[[Category: Lee, J]]
[[Category: Goldsmith EJ]]
[[Category: Michael, A J]]
[[Category: Lee J]]
[[Category: Phillips, M A]]
[[Category: Michael AJ]]
[[Category: Tomchick, D R]]
[[Category: Phillips MA]]
[[Category: Lyase]]
[[Category: Tomchick DR]]
Retrieved from "https://proteopedia.org/3n29"