4llj: Difference between revisions

<StructureSection load='4llj' size='340' side='right'caption='[[4llj]], [[Resolution|resolution]] 1.56&Aring;' scene=''>

<table><tr><td colspan='2'>[[4llj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LLJ FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.56&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1XN:2H-ISOINDOLE-1,3-DIAMINE'>1XN</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4llj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4llj OCA], [https://pdbe.org/4llj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4llj RCSB], [https://www.ebi.ac.uk/pdbsum/4llj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4llj ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PDE10_HUMAN PDE10_HUMAN] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.<ref>PMID:17389385</ref>  

*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Badger J]]

[[Category: Chie-Leon B]]

[[Category: Logan C]]

[[Category: Nienaber V]]

[[Category: Sridhar V]]