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==Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FI==
==Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FI==
<StructureSection load='4ca7' size='340' side='right' caption='[[4ca7]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
<StructureSection load='4ca7' size='340' side='right'caption='[[4ca7]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ca7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CA7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CA7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ca7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CA7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CA7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3EF:N-{(2S)-3-[(S)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-PHENYLETHYL](HYDROXY)PHOSPHORYL]-2-[(3-PHENYL-1,2-OXAZOL-5-YL)METHYL]PROPANOYL}-L-TYROSINE'>3EF</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ca5|4ca5]], [[4ca6|4ca6]], [[4ca8|4ca8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3EF:N-{(2S)-3-[(S)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-PHENYLETHYL](HYDROXY)PHOSPHORYL]-2-[(3-PHENYL-1,2-OXAZOL-5-YL)METHYL]PROPANOYL}-L-TYROSINE'>3EF</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidyl-dipeptidase_A Peptidyl-dipeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.15.1 3.4.15.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ca7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ca7 OCA], [https://pdbe.org/4ca7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ca7 RCSB], [https://www.ebi.ac.uk/pdbsum/4ca7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ca7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ca7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ca7 OCA], [http://pdbe.org/4ca7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ca7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ca7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ca7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACE_DROME ACE_DROME]] May be involved in the specific maturation or degradation of a number of bioactive peptides. May play a role in the contractions of the heart, gut and testes, and in spermatid differentiation.<ref>PMID:12591244</ref>
[https://www.uniprot.org/uniprot/ACE_DROME ACE_DROME] May be involved in the specific maturation or degradation of a number of bioactive peptides. May play a role in the contractions of the heart, gut and testes, and in spermatid differentiation.<ref>PMID:12591244</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Angiotensin-Converting Enzyme|Angiotensin-Converting Enzyme]]
*[[Angiotensin-Converting Enzyme 3D structures|Angiotensin-Converting Enzyme 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drosophila melanogaster]]
[[Category: Peptidyl-dipeptidase A]]
[[Category: Large Structures]]
[[Category: Acharya, K R]]
[[Category: Acharya KR]]
[[Category: Akif, M]]
[[Category: Akif M]]
[[Category: Beau, F]]
[[Category: Beau F]]
[[Category: Czarny, B]]
[[Category: Czarny B]]
[[Category: Dive, V]]
[[Category: Dive V]]
[[Category: Isaac, R E]]
[[Category: Isaac RE]]
[[Category: Masuyer, G]]
[[Category: Masuyer G]]
[[Category: Schwager, S L.U]]
[[Category: Schwager SLU]]
[[Category: Sturrock, E D]]
[[Category: Sturrock ED]]
[[Category: Hydrolase]]
[[Category: Inhibitor binding]]
[[Category: Zinc metallopeptidase]]
Retrieved from "https://proteopedia.org/4ca7"