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==Structure of hydroxyethylthiazole kinase protein from pyrococcus horikoshii OT3==
==Structure of hydroxyethylthiazole kinase protein from pyrococcus horikoshii OT3==
<StructureSection load='3hpd' size='340' side='right' caption='[[3hpd]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='3hpd' size='340' side='right'caption='[[3hpd]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hpd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrho Pyrho]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1v8a 1v8a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HPD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HPD FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1v8a 1v8a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HPD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.50 2.7.1.50] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hpd OCA], [http://pdbe.org/3hpd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hpd RCSB], [http://www.ebi.ac.uk/pdbsum/3hpd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hpd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hpd OCA], [https://pdbe.org/3hpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hpd RCSB], [https://www.ebi.ac.uk/pdbsum/3hpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hpd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THIM_PYRHO THIM_PYRHO]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hp/3hpd_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hp/3hpd_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pyrho]]
[[Category: Large Structures]]
[[Category: Transferase]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Jeyakanthan, J]]
[[Category: Jeyakanthan J]]
[[Category: Kuramitsu, S]]
[[Category: Kuramitsu S]]
[[Category: Structural genomic]]
[[Category: Tahirov TH]]
[[Category: Tahirov, T H]]
[[Category: Thamotharan S]]
[[Category: Thamotharan, S]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Alpha-beta]]
[[Category: Atp binding]]
[[Category: Atp-binding]]
[[Category: Kinase]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nucleotide-binding]]
[[Category: Rsgi]]
[[Category: Thiamine biosynthesis]]

Latest revision as of 15:52, 1 November 2023

Structure of hydroxyethylthiazole kinase protein from pyrococcus horikoshii OT3

3hpd, resolution 1.85Å

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